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Filtered Search Results
Medchemexpress LLC VTP50469 fumarate | 2169919-29-1 | 99.8% | 804.93 | 100 MG
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VTP50469 fumarate is a potent, highly selective, and orally active Menin-MLL interaction inhibitor. It demonstrates potent anti-leukemia activity with a Ki of 104 pM.
- Inhibits cell proliferation in MLL-r and ALL cell lines
- Induces apoptosis in MLL-r B cell ALL cell lines
- Causes dose-dependent differentiation in MLL-r AML cell lines
- Displaces Menin from protein complexes and inhibits chromatin occupancy of MLL
- Leads to changes in gene expression, differentiation, and apoptosis
- Shows significant survival advantage in in vivo studies in NSG mice
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TARGETMOL CHEMICALS INC TC-2216 5MG
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502693806 TC-2216 5MG
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Medchemexpress LLC TRPM8 antagonist 3 | 2102179-29-1 | 99.5% | C13H12N2O4S | 10MG
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TRPM8 antagonist 3 is a potent, selective small-molecule blocker of the TRPM8 ion channel used as a research tool to study cold-sensing and nociception pathways. It shows nanomolar potency (IC50 = 11 nM), a molecular formula of C13H12N2O4S, and is supplied as a high-purity material for in vitro and preclinical research.
- Potent TRPM8 channel blocker with IC50 = 11 nM.
- High purity suitable for research (99.5%).
- Supplied as a solid with option for DMSO solution for easy assay preparation.
- Intended for in vitro and preclinical studies of cold sensation and pain pathways.
- Available in multiple pack sizes to support different experimental scales.
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Medchemexpress LLC Cediranib maleate | 857036-77-2 | MFCD09954115 | 100.0% | C29H31FN4O7 | 10MG
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Cediranib maleate is the maleate salt of cediranib (AZD-2171), a potent orally available vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor supplied for research use. It is provided as a high-purity solid and is also available in ready-to-use DMSO stock solutions for biochemical and cell-based assays.
- High purity 99.95%.
- Potent VEGFR inhibitor with low-nanomolar activity against Flt1, KDR, Flt4, PDGFRα/β, and c-Kit.
- Suitable for in vitro and in vivo research applications.
- Supplied as a solid and as 10 mM DMSO solutions.
- Molecular formula C29H31FN4O7; molecular weight 566.58 Da.
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Medchemexpress LLC Flupirtine Maleate | 75507-68-5 | 100.0% | 420.39 | 100 MG
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Flupirtine Maleate is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. It functions as a neuronal potassium channel opener (Kv7 activator), an NMDA receptor antagonist, and a GABA receptor activator. This agent is suitable for research related to focal cerebral ischemia, pain, Alzheimer's disease, or multiple sclerosis.
- Stabilizes blood-brain barrier integrity.
- Reduces oxidative stress and brain leukocyte infiltration.
- Enhances angioneurogenesis.
- Suppresses calcium influx.
- Stabilizes neuronal resting membrane potential.
- Counteracts focal cerebral ischemia.
- Exhibits analgesic and muscle relaxant properties.
- Protects neurons from excitotoxic, ischemic, or cytokine-mediated death.
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Sigma Aldrich Fine Chemicals Biosciences Ethyl trans-2-decenoate >=95%, stabilized, FG | 7367-88-6 | MFCD00015299 | 100G
Ethyl trans-2-decenoate >=95%, stabilized, FG | Purity: >=95% | Mol Wt: 198.3 | 7367-88-6 | MFCD00015299 | 100G
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Sigma Aldrich Fine Chemicals Biosciences Ethyl trans-2-decenoate >=95%, stabilized, FG | 7367-88-6 | MFCD00015299 | 1KG
Ethyl trans-2-decenoate >=95%, stabilized, FG | Purity: >=95% | Mol Wt: 198.3 | 7367-88-6 | MFCD00015299 | 1KG
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Medchemexpress LLC Quipazine maleate 500mg | 500MG
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Quipazine maleate 500mg | 500MG
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Medchemexpress LLC Quipazine maleate | 5786-68-5 | 100 MG
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Quipazine maleate is a laboratory chemical from MedChemExpress, identified by catalog number HY-B1495 and CAS number 5786-68-5. It is intended for research use only and for experienced personnel. This product is classified as toxic if swallowed, requiring careful handling.
- Used for laboratory research and manufacturing of substances.
- Stable under recommended storage conditions.
- Shipping at room temperature is acceptable if less than 2 weeks.
- Recommended storage at 4°C, sealed, away from moisture and light.
- If in solvent, store at -80°C for 6 months or -20°C for 1 month.
- Appearance is a solid.
- Melting/freezing point is 151-154 °C.
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Pfaltz & Bauer DI(2-ETHYLHEXYL) FUMARAT 50G
Di(2-ethylhexyl) fumarate 50G CAS# 141-02-6
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Medchemexpress LLC U-99194 maleate | 234757-41-6 | MFCD01529985 | 99.2% | 393.47 g/mol | C21H31NO6 | 5 MG
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U-99194 maleate is a selective dopamine D3 receptor antagonist supplied as the maleate salt for research use. It is commonly used to probe D3-mediated signaling and motor disorder models, and is offered in small, research-sized quantities with reported high purity for biochemical and pharmacological studies.
- Selective dopamine D3 receptor antagonist useful for receptor pharmacology studies.
- Supplied as the maleate salt for stability and handling.
- High reported purity (99.2%) suitable for biochemical assays.
- Available in small milligram pack sizes for preclinical research.
- Characterized by molecular formula C21H31NO6 and molecular weight 393.47 g/mol.
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Medchemexpress LLC Asenapine maleate | 85650-56-2 | MFCD00900588 | 100.0% | 401.84 g/mol | C21H20ClNO5 | 5 MG
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Asenapine maleate is the maleate salt of asenapine, an atypical antipsychotic research compound that antagonizes multiple serotonin, dopamine, histamine, and adrenergic receptors. Supplied as a high-purity solid for laboratory research use. Molecular formula C21H20ClNO5; molecular weight 401.84 g/mol; CAS 85650-56-2. Not for human or veterinary use.
- High reported purity suitable for analytical and biochemical assays.
- Multi-receptor antagonist profile for studies of 5-HT, D2, H1, and adrenergic signaling.
- Solid form with defined small pack sizes for dose-response experiments.
- Accompanied by datasheet and certificate of analysis for batch-specific quality information.
- Intended for research use only; not for human or veterinary use.
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eMolecules (S)-3-Amino-2-methylpropanoic acid | 4249-19-8 | MFCD07372875 | 250mg
Ambeed | (S)-3-Amino-2-methylpropanoic acid | 250mg | 490545945 | A262596 | | 4249-19-8 | MFCD07372875 | 103.121 | C4H9NO2
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![eMolecules Synthonix / methyl 1-amino-6-bromoisoquinoline-4-carboxylate / 250mg / 779537019 / AC78107 / / 2090332-56-0 / [null] / 281.109 / C11H9BrN2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502478617.JPG-250.jpg)
eMolecules Synthonix / methyl 1-amino-6-bromoisoquinoline-4-carboxylate / 250mg / 779537019 / AC78107 / / 2090332-56-0 / [null] / 281.109 / C11H9BrN2O2
Synthonix / methyl 1-amino-6-bromoisoquinoline-4-carboxylate / 250mg / 779537019 / AC78107 / / 2090332-56-0 / [null] / 281.109 / C11H9BrN2O2
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Medchemexpress LLC Diethyl maleate | 141-05-9 | MFCD00009191 | 98.1% | 172.18 g/mol | C8H12O4 | 500mg
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Diethyl maleate (DEM) is an orally available effective glutathione (GSH) depletor that crosses the blood-brain barrier Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0 1-0 5 mM Diethyl maleate selectively depletes GSH in liver lung and brain tissues exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO- Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3]
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